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Preserving muscle helps support long-term weight stability

While the exact mechanism remains unproven, several hypotheses exist regarding how incretin-based therapies might potentially influence pancreatic inflammation: Gallstone formation : Rapid weight loss associated with tirzepatide may increase cholesterol saturation in bile, raising gallstone riska known precipitant of pancreatitis

A rare but significant concern is medullary thyroid carcinoma, as well as multiple endocrine neoplasia syndrome type 2 (MEN 2), and any family history of these conditions should be discussed prior to treatment with Zepbound

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Ozempic exclusively targets GLP-1 receptors