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In animal models of obesity, baseline serotonin release from the hypothalamus was found to be lower [91]

Association between characteristics of behavioural weight loss programmes and weight change after programme end: systematic review and meta-analysis

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GLP-1 patches are designed to deliver medication continuously through the skin, maintaining steady drug levels, whereas injections create peak-and-trough concentration patterns

Research in earlier phases or small trials include evaluation of GLP-1s for indications such as cystic fibrosis-related diabetes, polycystic ovarian syndrome (PCOS), chronic obstructive pulmonary disease (COPD), Prader-Willi syndrome (PWS), asthma, substance or alcohol use disorder, and as add-on to insulin for type 1 diabetes