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European Medicines Agency (EMA)

Prior health conditions You may not be a good candidate for GLP-1 agonists, depending on your health history

2017;33:e2924

S1A, GLP-1RA intervention was associated with a reduction in BMI when compared to metformin (MD = 1.11

Studied doses typically range from 900 to 1,500 mg daily, divided into two or three doses to minimize gastrointestinal side effects, though it's important to note that berberine has poor and variable oral bioavailability
