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doi: 10.1038/s41467-020-14309-w 24 IshibashiYMatsuiTTakeuchiMYamagishiS

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Compounded semaglutide may include additional ingredients (such as vitamins) or different salt forms of semaglutide, which the FDA does not approve for compounding

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Patients at higher risk for dehydration complications include older adults, individuals with chronic kidney disease, those taking diuretics or other medications affecting fluid balance, and patients with diabetes who may have underlying autonomic dysfunction affecting thirst perception