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For the analyses with different lag periods after starting treatment, the hazard ratio for thyroid cancer was 0.83 (95% confidence interval 0.56 to 1.22) with a one year lag and 0.90 (0.58 to 1.38) with a two year lag
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Phase 2 and interim phase 3 clinical trial data demonstrate robust effectiveness of GLP-1 RAs in achieving MASH resolution, with semaglutide showing additional promise for fibrosis improvement in the ongoing ESSENCE trial

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