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Stopping cold often leads to gradual rebound, which is consistent with how all incretin therapies behave

Its particularly important for regulating energy metabolism genes rather than developmental or reproductive pathways, making it distinct in research focused on cellular energetics rather than hormonal signaling

This medicine may increase the risk of these tumors

At maximum doses, both medications produce similar results (around 20% weight loss), so increasing your Wegovy dose may achieve comparable outcomes without changing medications

Planning Pregnancy: When to Stop Tirzepatide Therapy Most reproductive health specialists recommend discontinuing tirzepatide at least one to three months before attempting to conceive, though some providers may suggest longer washout periods depending on individual circumstances