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In the SURPASS-2 trial, the active ingredient in Zepbound medication was found to be superior to semaglutide in regards to the mean change in the glycated hemoglobin level with the added effect of weight reduction
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For example, a literature review performed in 2024 found only two case reports of GLP-1 RAs for treating HS that met the inclusion criteria

Managing these side effects proactively, rather than just tolerating them, is key to long-term adherence

If these issues last longer, speak with a doctor, as it may mean that the IUD is not in the correct place
