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The gap between trial and real-world tirzepatide vs semaglutide outcomes comes mostly from discontinuation and under-titration: only 25.9% of tirzepatide users reach 15 mg in practice, versus 83.5% of semaglutide users reaching 2.4 mg in the trial

2012;97 doi: 10.1210/jc.2011-3018
Buenaventura, T

According to a December 2025 YouGov survey, exercising more ranked as the top New Year's resolution for 2026, cited by 25 percent of U.S
Patients with chronic pancreatitis (CP) is one of the major risk groups for pancreatic cancer, and the relative risk of pancreatic cancer in patients with CP has been reported to be as high as 7.668.1 times 2,3,4,5,6
