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One small additional consideration is tolerability, particularly around progesterone formulation

Remember that GLP-1 injectable medications can be administered regardless of meal timing, while oral semaglutide (Rybelsus) must be taken on an empty stomach with a small sip of water (120ml) at least 30 minutes before eating, drinking or taking other oral medicines

And, in people who may be struggling with the emotional effects of worrying about their weight and health, I have found that moving around in the world about them is a bridge into the active and engaged life that they usually desire. Snyder says that exercising outdoors also has meaningful mental health benefits, such as reductions in stress, improved mood, and better adherence to exercise routines