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A quick recap: how GLP-1 medications work GLP-1 receptor agonists mimic a natural hormone called glucagon-like peptide-1, which is released in the gut after eating

McGraw-Hill / Lange rxlist.com (Tragenta ) Alogliptin Trade Name: Nesina Mechanism of Action: a DPP-4 inhibitor, similar to Sitagliptin Pharmacokinetics: does not undergo significant metabolism, and is mostly excreted unchanged in the urine (76%) and feces (13%) dosage should be reduced in patients with moderate to severe renal impairment References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)

Genetic context complementsrather than replacesmedical evaluation and provider judgment

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The increased prevalence indicates the need for novel therapeutic strategies and supportive care to manage the symptoms of these neurodegenerative diseases and to improve the quality of life for the affected individuals