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The FDA cautions that during clinical trials, some patients had decreased sweating and their base temperature increased

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For instance, as per Princess Nourah bint Abdulrahman University, Saudi Food and Drug Authority (SFDA) biologics approval in Saudi Arabia increased from 5 approvals during 2005-2009 to 38 approvals during 2015-2019

CNS-intrinsic events may trigger disease development, with the infiltration of autoreactive lymphocytes as a secondary phenomenon [112]
