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Batterham RL, Cohen MA, Ellis SM, Le Roux CW, Withers DJ, Frost GS, et al

IGFs and IGF signaling have a key role in growth and cell proliferation, and deregulation of these processes contributes to the pathogenesis of multiple diseases 45

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Semaglutide was approved for weight management in 2021, while tirzepatide followed in 2023
While effective, they come with notable side effects, including nausea, digestive issues and some serious issues : Vision Impairment Alert Semaglutide, a widely used GLP-1 receptor agonist, has been linked to a significantly higher rate of reported vision problems
