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The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study

The certainty of evidence was low for weight outcome and very low for the remaining outcomes

This triple mechanism of action distinguishes it from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 receptor agonist)

Nakamura T, Harada K, Kamiya T, Takizawa M, Kppers J, Nakajima K, et al

If a specific numerical figure is provided, it should be emphasised that this advice is for the meal immediately following injection to avoid the risk of undernourishment