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Nat Med 2015;21:27-36.PubMed 27

36 In 2012, the extended-release (ER) formulation of exenatide (Bydureon , Amylin Pharmaceuticals) was approved by the US FDA to treat type 2 diabetes mellitus

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Furthermore, in the high cardiovascular-risk population of the SURPASS-4 trial, reductions in triglycerides, LDL cholesterol, and total cholesterol, and increases in HDL cholesterol were observed in all of the tirzepatide participating groups [10]

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