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Participants who stopped after achieving substantial weight loss experienced gradual regain over the following year
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But I hope that this nuance
Phase 2 trial data (NEJM, 2023) showed a mean body weight reduction of approximately 24% at the highest dose (12 mg weekly) over 48 weeks in adults without type 2 diabetes
Vegetables and fruit still need to be included even when appetite is low
The triple receptor mechanism of retatrutide, particularly the glucagon receptor component, contributes to higher GI side effect rates overall
