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[email protected] OPEN ACCESS PUBLISHED: 30 April 2026 CITATION Joshi, A., and Li, D., 2026

oral regimens), and trial endpoints better tuned to metabolic mechanisms

It operates by mimicking a hormone that regulates appetite, which can lead to []
in The Journal of Headache and Pain, and Bade et al

they may also have direct effects in the brain (animal studies show neuroprotection and reduced amyloid/tau pathology)
