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Inflammatory cytokines, such as TNF-, IL-18, and IL-6, are significantly elevated in patients with PCOS compared with healthy individuals.16 Macrophages and lymphocytes in the ovarian tissue of PCOS patients secrete large amounts of TNF- and IL-6, resulting in inhibition of the formation of dominant follicles and apoptosis of granulosa cells

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They work by mimicking the effects of the GLP-1 hormone, which regulates blood sugar levels, appetite, and metabolism

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