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in multiple mouse models of obesity, this led to a decrease in body weight and the correction of dyslipidemia [141]

Interestingly, small intestinal mass also increases proportionally to the temperature drop 6

The full effects become more evident once the higher doses are introduced, so weight loss may speed up after the first month or two of treatment
These include SGLT2 inhibitors, optimised insulin regimens, structured education programs and targeted lifestyle support

Science 308, 16351638
