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The SURMOUNT-5 trial directly compared tirzepatide to semaglutide, demonstrating superior weight loss outcomes at equivalent therapeutic doses

Liu P-S, Chen Y-T, Li X, Hsueh P-C, Tzeng S-F, Chen H, et al

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But Gabbay said the difference in weight reduction between the new trial and the nondiabetes trial is consistent with other weight loss medication research
The timeline for side effect improvement is comparable
