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CGM-measured glucose values have a strong correlation with C-peptide, HbA1c and IDAAC, but do poorly in predicting C-peptide levels in the two years following onset of diabetes
Why women need a female-specific retatrutide dosing approach Pharmacokinetics differ by sex The assumption that one dose fits all has caused real harm in weight-loss pharmacology
It underscores why the CagriSema vs retatrutide debate remains active
In 2023 Lilly published results of its phase 2 trial for orforglipron, a once-daily oral drug which achieved up to 14.7% mean weight reduction at 36 weeks, and Pfizer has completed phase 2 trial for its oral drug danuglipron and is now optimising the formulation
When dealing with a persistent injury that hasn't improved despite activity modification and rehab, peptides may offer a solution
