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As patients lose substantial amounts of adipose tissue, their body's natural insulation decreases, potentially making them more susceptible to environmental temperature changes

Press Release 26 July 2013

Third, the clinical hypothesis that TRT could preserve lean mass during GLP-1 therapy in men with persistently low testosterone is mechanistically plausible yet empirically untested

JAMA 327(2):138150 Bergmann NC et al (2023) Semaglutide for the treatment of overweight and obesity: a review
