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[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Wadden TA, Bailey TS, Billings LK, et al

Liver Function Parameters (Table 2b,c, Figure 3) Liver enzymes and markers of hepatic synthetic function improved significantly in the semaglutide group, suggesting reduced hepatic inflammation and preserved liver function

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Inducible reporter assays, especially luciferase reporters, which are linked to the activation of specific signaling pathways for example by the GIP receptor, provide a reliable measurement of the inhibitory or activating effect of substances on diabetes-associated cell signaling pathways (Fig