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A comprehensive pre-treatment evaluation includes thyroid antibody status, current levothyroxine dose adequacy, gastrointestinal history, and family history of thyroid or endocrine disease

Many of the more severe side effects people worry about tend to occur when dosing is escalated aggressively or when patients remain on unnecessarily high doses

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Those who stick with their plan beyond 8 weeks often notice progress picking up speed around the third month

There is no clinical evidence that alternating produces more total weight loss than optimizing a single medication