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128-OR: the effect of tirzepatide during weight loss on food intake, appetite, food preference, and food craving in people with obesity

The triple agonist mechanism appears to match or slightly exceed tirzepatide for blood sugar management , likely because the glucagon component, while it can raise blood sugar in isolation, works synergistically with GLP-1 and GIP activation to produce a net positive effect on glucose regulation

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The dose-dependent effect observed in this meta-analysis further confirms previous reports on tirzepatides efficacy (36, 37, 39)

second, we evaluated the effectiveness of each agent in populations expanded to those treated in routine care
