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Methods: We did a 56-week, phase 3a, randomised, double-blind, double-dummy, active-controlled, parallel-group, multinational, multicentre trial (SUSTAIN 2) at 128 sites in 18 countries

FIGURE 10 3.6 Validation of the expression of GLP-1 signaling-related genes in CRC tissues Subsequently, we performed protein-protein interaction network analysis among 42 genes related to GLP-1 signaling (Supplementary Figure S1) and selected top 10 genes with highest node-degree for further validation in CRC tissues (Supplementary Table S2)

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doi: 10.1111/dom.13634

They were from five NEN types: duodenal NETs (dNETs), gastric NETs, pancreatic NETs, pheochromocytomas, and lung NETs