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Changes in the ratio of cortical R2* and medullary R2* also did not vary significantly between SGLT2 inhibitor users and nonusers in both semaglutide and placebo groups ( P -interaction=0.88 and P -interaction=0.84, respectively)
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Using that as a template, the first GLP-1 agonist was created and approved for the treatment of diabetes about 20 years ago
