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Description
The glucagon receptor arm the feature that distinguishes retatrutide from earlier-generation incretin compounds drives hepatic glucose metabolism, lipid oxidation, and energy expenditure effects, all absent from GLP-1 mono-agonists and dual GLP-1/GIP agonists

Patients on Wegovy may reach a maintenance dose of 2.4 mg, while Ozempics maximum dose is 2 mg

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Three core barriers prevent broader and faster progress: medication cost, medication side effects, and the lack of sustainable behavior change
A few slower days or a quiet week on the scale usually reflects these normal ups and downs rather than a loss of progress
