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In absolute terms, the primary composite occurred in 0.7% of GLP-1 users and 1.8% of never-users during days 91365, corresponding to approximately one fewer event per 100 patients

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Summary Retatrutide, a triple agonist now in phase 3 trials, has the potential to become the most effective pharmacological treatment for obesity while also offering substantial benefits in T2D management and other cardiometabolic risk factors.

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