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The upcoming Phase I/II clinical trial will test the safety and preliminary efficacy of RJVA-001, a gene therapy designed to locally deliver GLP-1 receptor agonist drugs with the goal of reducing the side effects associated with oral administration

doi: 10.1161/CIRCULATIONAHA.111.087213
Lowering your total body weight before surgery makes the operative procedure substantially safer and reduces the risk of complications

Chen C, Zhou R, Fu F, Xiao J (2023) Postmarket safety profile of suicide/self-injury for GLP-1 receptor agonist: a real-world pharmacovigilance analysis

[DXA substudy: lean tissue approximately 40% of total weight lost.] Look M, et al
