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By decreasing the production rate of estrogen and limiting its concentration within patients' systems, it manifests potential as a solution against hormone-sensitive types of breast cancer growth or involvements with infertility cases through ovulation promotion functioning capabilities
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Finally, following recent concerns by regulatory agencies regarding a potential increase in suicidal behavior associated with GLP-1RAs 206 , we found 1 recent pharmacovigilance report showing 0.6% suicidal events among 41,236 safety reports for these medications 207 and an emulated target trial of 86,418 older adults with T2DM that did not identify any difference in suicidal ideation or behavior between GLP-1RAs and other antidiabetic medications over 1.5 years 208