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That being said only 4.1 % of patients stopped the 4mg dose which is less than the placebo arm

Furthermore, targeted delivery of exendin-4 to the nucleus of the solitary tract (NTS) similarly diminished both operant responding for sucrose under a progressive ratio schedule and conditioned place preference for food rewards in rats (Richard et al., 2015)

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An observational cohort study involving 168 pregnant women exposed to GLP-1 receptor agonists during the first trimester found a 2.6% prevalence of major birth defects, comparable to 2.3% in the diabetic reference group