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However, in patients like him, who also suffer from hypothyroidism and are on levothyroxine (thyroid hormone replacement), such a drastic weight reduction can lead to over-medication of the thyroid

Mol Cell Endocrinol 141 , 179186 (1998)
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Notably, studies on tendon fibroblasts revealed dose-dependent increases in growth hormone receptor expression, with up to sevenfold elevations observed by the third day of study