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As of 2026, Mounjaro (tirzepatide) is an established once-weekly injection in the UK for adults with obesity, or overweight with a weight-related comorbidity, used alongside a reduced-calorie diet and increased physical activity

Current 2024 multi-society guidance suggests most patients can continue GLP-1 agonist therapy with appropriate risk stratification rather than routine holds

2023 Lillys Zepbound (tirzepatide) is approved for weight management

Novel perspectives on the link between obesity and cancer risk: from mechanisms to clinical implications