is trulicity a glp 1 inhibitor GLP-1 Agonists - What it? List of approved and pending
Description
arrestinsPositive or negative regulators of GLP1 receptor signalling
Dual GIP/GLP-1 agonists add GIP receptor activation, which: Amplifies insulin secretion beyond what GLP-1 alone achieves Increases insulin sensitivity in peripheral tissues Appears to shift adipocyte metabolism toward fat oxidation (mechanism still under investigation) May reduce the nausea signal that limits GLP-1 dose escalation (GIP has anti-emetic properties in animal models) The weight loss ceiling for tirzepatide is approximately 20% to 22% of baseline body weight at the 15 mg dose over 72 weeks (SURMOUNT-1 data)
Do I think it broadens the segment of the population who actually will finally be diagnosed and look for treatment
Optional: 2 oz smoked salmon on top for an extra protein boost (add 12g protein)
What would you recommend that they first take a look at and really unpack before jumping to this medication
