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PIONEER 1: Randomized clinical trial of the efficacy and safety of oral GLP1 monotherapy in comparison with placebo in patients with type 2 diabetes

While there are no strict food restrictions, avoiding high-fat, greasy, or very large meals can help reduce gastrointestinal side effects

The needle went deeper than expected

This gradual release can be easier on the gastrointestinal system compared to immediate-release formulations

Your obesity-related comorbidities (like sleep apnea) require more aggressive weight reduction, and you can tolerate a slightly elevated side effect profile
