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side effects to glp 1 Potential metabolic and mechanism of GI effects of GLP-1 GLP-1 Gut Side Effects: Bloating
Description
We have an obligation to understand the full biology of these drugs, not just the intended effect

This means if you lose 20 pounds on a GLP-1, as much as 8 pounds could be muscle or other lean tissue

Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND)

Whether continued GCGR-mediated energy expenditure explains the sustained trajectory is not yet formally characterised, but the mechanistic hypothesis is consistent with the animal data

It increases receptor overstimulation and the severity of side effects, particularly nausea and cardiovascular effects
