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The sum of those benefits is what can lead to weight loss for some people

It may present with a spectrum of symptoms, including as an incidental finding on cardiothoracic imaging or a severe chest and back pain, like an aortic dissection

Participants who had not lost at least 5% of their starting body weight by week 12 rarely achieved robust results by week 48

Combining these approaches warrants further research to fully understand long-term outcomes

10.3389/fncel.2016.00214 Front Cell Neurosci