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10.1172/jci142243 121 TomitaT

Appetite changes often come first, followed by visible weight loss once dosing increases and the body adapts

Cimetidine is a known inhibitor of hepatic CYP enzymes and reduces the metabolism of sildenafil

Patients who should exercise particular caution Several autoimmune patient groups warrant extra caution

Endocrinology 154: 127139, 2013
