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[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Tondt J, Freshwater M, Benson-Davies S, et al

Nausea is typically most pronounced during dose escalation and often improves with continued use as physiological tolerance develops

When controls were placed on a high-fat diet for 6 weeks they became just as hyperglycaemic and glucose intolerant as the knock-in mice