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[DOI] [PubMed] [Google Scholar] 72.Li R, Mai T, Zheng S, Zhang Y

2000;278:E1010E1018

In the past ten years, a series of Phase III trials showed that the synthetic GLP-1/GIP agonists are effective in lowering blood sugar in type 2 diabetic subjects who were both treatment-nave or on typical first-line therapies such as metformin and insulin

Toft-Nielsen MB, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, et al

Consequently, weight loss facilitates improved blood pressure control and reduces the progression of albuminuria and DKD [85]
