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Improved glycaemic control with minimal hypoglycaemia and no weight change with the once-daily human glucagon-like peptide-1 analogue liraglutide as add-on to sulphonylurea in Japanese patients with type 2 diabetes

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It is appropriate for select patients who are good candidates for a more aggressive protocol

First, establish baseline parameters including fasting glucose, HbA1c, comprehensive metabolic panel (assessing renal and hepatic function), and lipid profile

The key distinction: semaglutide acts on specific peptide-signaling cascades, while ashwagandha influences broader neuroendocrine and immune responses