who discovered glp 1 agonists A future Nobel Prize? Looking back to the discovery history of GLP-1 drugs such as Evolution of GLP‐1 Receptor Agonists

The stimulation of amylase secretion by GLP-1 may not have physiological importance as the concentrations of peptide required are higher than seen in peripheral blood

The results provide insights into the benefits and risks of GLP-1RAs and may be useful for informing clinical care and guiding research agendas

GLP-1 increases insulin and decreases glucagon levels, which will result in decreased blood glucose [8, 9]

NAFLD, Non-alcoholic fatty liver disease

Collective data from major clinical trials have shown that treatment with a DPP-4i improves glycemic control by increasing insulin secretion from islet cells, lowering levels of HbA1c, reducing adipocyte size, and suppressing inflammation [4751]