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That extra GCGR component is why retatrutide is often discussed as a potential extension of the dual-agonist concept rather than a simple copy of it

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States may choose to start participating in BALANCE starting on a date of their choosing between May 1, 2026, and January 1, 2027

Keep your provider informed about symptom patterns, as persistent issues may warrant evaluation for conditions like gastroparesis, which has been reported in association with GLP-1 receptor agonists
