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There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

One of the most interesting human studies in my opinion is a pooled analysis of seven clinical trials involving 1,094,761 patients (both men and women around 60 years old), selected from a U.S
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2,4 Emerging studies indicate that GLP-1 may also contribute to the health of the gut microbiome

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Wilding Diabetes Therapy.2019