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Some patients report changes in appetite or food cravings during the transition period, though these effects are generally temporary and related to the physiological adjustments rather than withdrawal symptoms
But regardless of why someone stops, the next part is often predictable: The weight tends to come back
doi: 10.1093/ije/dyu038
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The dose-dependent weight-loss effects were notable (79.5 kg greater than with placebo in the SURPASS 1 trial, which evaluated tirzepatide vs placebo in patients with T2D) [69]
