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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Dejgaard T.F., Frandsen C.S., Hansen T.S., Almdal T., Urhammer S., Pedersen-Bjergaard U
Accessed on February 14, 2021 at MedlinePlus

Discard the medication immediately if you observe any of the following: Particulate matter Color changes such as darkening or browning Crystallization Changes in viscosity These physical changes indicate chemical degradation or contamination
Common Side Effects: Nausea : This is the most common side effect and usually occurs when starting the medication or after increasing the dose

She likens the phenomenon to insulin resistance, which is still not fully understood decades after its discovery
