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In SURMOUNT-1, the landmark trial for tirzepatide in weight management, participants without diabetes achieved the following results over 72 weeks: 5 mg dose: 16.0% average body weight reduction 10 mg dose: 21.4% average body weight reduction 15 mg dose: 22.5% average body weight reduction Read that again

If you are transitioning between subcutaneous injection formulations with different volumes, note that larger volumes may produce more local irritation