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A patient beginning at 0.25mg semaglutide may reach 1mg, 1.7mg, or 2.4mg by month four or five

Endogenous GLP-1 is rapidly degraded primarily by dipeptidyl peptidase-4 (DPP-4), as well as neutral endopeptidase 24 } : CS1 maint: DOI inactive as of July 2026 (link) Journal of Diabetes

J., Rechlin, R
S., Kim, H

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