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Its receptor binding profile shows that it binds to GIP receptors with an affinity similar to the natural hormone but has a fivefold lower affinity for GLP-1 receptors

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It works by increasing levels of key brain chemicals like norepinephrine, dopamine, and serotonin, which can help suppress appetite, reduce emotional eating, and support sustained daily energy.

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The primary outcome was the risk of new ED diagnosis and/or new prescription of phosphodiesterase type 5 inhibitors at least one month after prescription of semaglutide