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Early study results have shown very significant weight loss outcomes, but the medicine must complete further research and pass regulatory assessment before it can be prescribed in the UK

It is associated with significant complications of multiple organ systems, including the eyes, nerves, kidneys, and blood vessels

Others have demonstrated that the positive outcomes of obesity surgery (i.e., changes in body weight and improved glucose homeostasis) are sustained in mice in the absence of GLP-1R or Y2-R, or both GLP-1R and Y2-R 66,67
